Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16668184 | 0.66 | BACE1 (0.32) | — | |
| SCHEMBL16668457 | 0.66 | — | — | |
| SCHEMBL16668540 | 0.65 | — | — | |
| SCHEMBL16668488 | 0.64 | BACE1 (0.32) | — | |
| SCHEMBL25280121 | 0.57 | BACE1 (0.37) | — | |
| SCHEMBL27152796 | 0.57 | BACE1 (0.37) | — | |
| SCHEMBL6332883 | 0.56 | BACE1 (0.32) | — | |
| SCHEMBL325378 | 0.55 | CXCR4 (0.39) | — | |
| SCHEMBL16668121 | 0.55 | ALDH1A1 (0.37) | — | |
| SCHEMBL16668453 | 0.55 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060563-A1 | RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS | Novartis AG (CH) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015059668-A1 | RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS | NOVARTIS AG (CH) | 2015-04-30 | — | — | WO | disclosed |