⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2224043 | 0.80 | — | — | |
| SCHEMBL1742345 | 0.78 | — | — | |
| SCHEMBL9393588 | 0.78 | POLB (0.30) | — | |
| SCHEMBL2910490 | 0.74 | PDK1 (0.41) | — | |
| SCHEMBL6299910 | 0.74 | — | — | |
| SCHEMBL2918826 | 0.74 | — | — | |
| SCHEMBL4681297 | 0.74 | — | — | |
| SCHEMBL2780816 | 0.71 | — | — | |
| SCHEMBL839800 | 0.71 | — | — | |
| SCHEMBL25879395 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742300-A | Pharmaceutical composition | 纽罗普罗治疗股份有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-106459022-B | The preparation method of antifungal compound | 北卡罗来纳维亚梅特制药公司 | 2019-08-02 | — | — | CN | claimed |
| CN-110003135-A | The preparation method and its synthetic intermediate of solanone | 长谷川香料株式会社 | 2019-07-12 | — | — | CN | claimed |
| CN-109963466-A | The method for managing herbicide evaporation | 阿格夸姆公司 | 2019-07-02 | — | — | CN | claimed |
| CN-109762642-A | A kind of low conductance coolant liquid and preparation method thereof | 中国船舶重工集团公司第七一八研究所 | 2019-05-17 | — | — | CN | claimed |
| CN-108347949-A | antifungal compound method | VPS-3公司 | 2018-07-31 | — | — | CN | claimed |
| CN-108289457-A | Antifungal compound preparation method | 迈科维亚医药公司 | 2018-07-17 | — | — | CN | claimed |
| CN-107721815-A | The preparation method of one kind 2 (3,5 2 (trifluoromethyl) phenyl) 2 methylpropanoic acids of synthesis | 爱斯特（成都）生物制药股份有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-107001325-A | O-formamido benzamide compound and application thereof | 江苏中旗作物保护股份有限公司 | 2017-08-01 | — | — | CN | claimed |
| CN-106459022-A | Antifungal compound process | 维亚梅特制药公司 | 2017-02-22 | — | — | CN | claimed |
| WO-2004078128-A2 | SUBSTITUTED PYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-09-16 | — | — | WO | claimed |
| US-6743927-B2 | PROCESS FOR ENANTIOSELECTIVELY PRODUCING THE (R)-DELTA-LACTONE | ROCHE COLORADO CORPORATION | 2004-06-01 | — | — | US | claimed |
| US-20030171602-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION | 2003-09-11 | — | — | US | claimed |
| US-20030158422-A1 | Process for enantioselectively producing the (R)-delta-lactone | ROCHE COLORADO CORPORATION | 2003-08-21 | — | — | US | claimed |
| US-20030158423-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION (US) | 2003-08-21 | — | — | US | claimed |
| JP-2003521546-A | — | — | 2003-07-15 | — | — | JP | claimed |
| US-6545165-B1 | Cyclization | ROCHE COLORADO CORPORATION | 2003-04-08 | — | — | US | claimed |
| EP-1255747-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-11-13 | — | — | EP | claimed |
| WO-2001057014-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-09 | — | — | WO | claimed |
| US-3984552-A | 6-Oxo-7-substituted and 7,7-disubstituted-6H-indeno-[5,4-b]furan (and thiophene) carboxylic acids | MERCK & CO., INC. (US) | 1976-10-05 | — | — | US | claimed |