Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491987 | 1.00 | CHRNB2 (0.43) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL1531109 | 0.97 | — | — | |
| SCHEMBL12631398 | 0.92 | CYP1A2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL1857022 | 0.92 | CYP1A2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL1859619 | 0.92 | CYP1A2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL20329687 | 0.84 | CHRM2 (0.37) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL974399 | 0.83 | CHRM2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL974400 | 0.83 | CHRM2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL974796 | 0.83 | CHRM2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 | |
| SCHEMBL8494369 | 0.83 | CHRM2 (0.48) | CHRNB2CHRNA4CYP1A2HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018408-B2 | Processes for producing terephthalic acid and terephthalic esters | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-04-28 | — | — | US | disclosed |