Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 15/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 2/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17004633 | 0.85 | KCNH2 (0.53) | MAP4K4 | |
| SCHEMBL17004641 | 0.84 | KCNH2 (0.51) | CHEK2FYNMAP4K4 | |
| SCHEMBL19086089 | 0.77 | LRRK2 (0.60) | — | |
| SCHEMBL12516852 | 0.75 | CHEK2 (0.88) | CHEK2MKNK1FYNMAP4K4CHEK1 | |
| SCHEMBL4620246 | 0.73 | CHEK2 (1.00) | CHEK2MKNK1FYNMAP4K4CHEK1 | |
| SCHEMBL2227506 | 0.72 | KCNH2 (0.77) | CHEK2MKNK1FYNMAP4K4CHEK1 | |
| SCHEMBL2228006 | 0.71 | CHEK2 (0.75) | CHEK2MKNK1FYNMAP4K4CHEK1 | |
| SCHEMBL12518024 | 0.71 | KCNH2 (0.62) | CHEK2MKNK1FYNMAP4K4CHEK1 | |
| SCHEMBL18613241 | 0.71 | FYN (1.00) | CHEK2MKNK1FYNMAP4K4CHEK1 | |
| SCHEMBL1633511 | 0.70 | DRD3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024033-B2 | Anti-malarial agents | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2015-05-05 | — | — | US | disclosed |