Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.47 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | IL2 | P60568 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16673188 | 1.00 | ACE (0.47) | ACEMMEFOLH1NAALAD2SLC7A5 | |
| SCHEMBL16673455 | 0.91 | ACE (0.46) | ACE | |
| SCHEMBL4177756 | 0.91 | ACE (0.46) | ACE | |
| SCHEMBL16673180 | 0.88 | CA2 (0.43) | CA2ALBIL2 | |
| SCHEMBL16673178 | 0.88 | CA2 (0.43) | CA2ALBIL2 | |
| SCHEMBL23598458 | 0.84 | SLC7A5 (0.48) | ACEMMESLC7A5CPA1ACE2 | |
| SCHEMBL4434143 | 0.84 | SLC7A5 (0.48) | ACEMMESLC7A5CPA1ACE2 | |
| SCHEMBL9664998 | 0.84 | SLC7A5 (0.48) | ACEMMESLC7A5CPA1ACE2 | |
| SCHEMBL9665005 | 0.84 | SLC7A5 (0.48) | ACEMMESLC7A5CPA1ACE2 | |
| SCHEMBL4434130 | 0.84 | SLC7A5 (0.48) | ACEMMESLC7A5CPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041157-B1 | PEPTIDE DERIVATIVES WITH THERAPEUTIC ACTIVITY | FLAMMA SPA (IT) | 2015-05-06 | — | — | EP | claimed |