SCHEMBL16673267

SCHEMBL16673267

COc1ccc(C(=O)c2cc(S(=O)(=O)O)c(OC)c(S(=O)(=O)O)c2O)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.58
RAB9A P51151 5/20 0.58
LMNA P02545 5/20 0.52
CYP3A4 P08684 4/20 0.52
HPGD P15428 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP1A2 P05177 2/20 0.52
PGR P06401 2/20 0.52
SLC6A2 P23975 2/20 0.52
ADORA3 P0DMS8 1/20 0.52
AR P10275 1/20 0.52
CHRM1 P11229 1/20 0.52
ALOX15 P16050 1/20 0.52
TBXA2R P21731 1/20 0.52
ADRA1A P35348 1/20 0.52
HIF1A Q16665 1/20 0.52
ALDH1A1 P00352 4/20 0.48
MAPK1 P28482 4/20 0.48
CYP2D6 P10635 1/20 0.48
PDE4A P27815 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31634969 1.00 NPC1 (0.58) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL4384109 0.99 NPC1 (0.57) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL9762530 0.87 NPC1 (0.65) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL30214285 0.87 NPC1 (0.57) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL6334068 0.82 NPC1 (0.73) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL28099195 0.81 NPC1 (0.48) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL8427070 0.81 NPC1 (0.63) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL28708553 0.80 NPC1 (0.47) NPC1RAB9ALMNACYP3A4HPGD
SCHEMBL7129528 0.80 NPC1 (0.61) NPC1RAB9ALMNACYP3A4HPGD
Sulfuric Acid SCHEMBL9740504 0.80 NPC1 (0.86) NPC1RAB9ALMNACYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3215108-A1 HAIR DYE Henkel AG & Co. KGaA (DE) 2017-09-13 EP disclosed
WO-2016072062-A1 HAIR DYE HENKEL AG & CO. KGAA (DE) 2016-05-12 WO disclosed
EP-2868312-A1 HAIR-DYE COMPOSITION FUJI-FILM Corporation (JP) 2015-05-06 EP disclosed