Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427070 | 0.88 | NPC1 (0.63) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL31634969 | 0.87 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL16673267 | 0.87 | NPC1 (0.58) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL7129528 | 0.87 | NPC1 (0.61) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL4384109 | 0.86 | NPC1 (0.57) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL6334068 | 0.86 | NPC1 (0.73) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| Sulfuric Acid SCHEMBL9740504 | 0.84 | NPC1 (0.86) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL952977 | 0.82 | LMNA (0.71) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL30214285 | 0.81 | NPC1 (0.57) | NPC1RAB9ALMNAHPGDCYP2C19 | |
| SCHEMBL414485 | 0.81 | MAPT (0.66) | NPC1RAB9ALMNAHPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053222-A | Antidandruff agents | SHISEIDO COMPANY LTD. (JP) | 1991-10-01 | — | — | US | disclosed |