Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 7/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TLR2 | O60603 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexacosanoic Acid SCHEMBL30380127 | 1.00 | PAOX (0.62) | PAOXGPR84PPARGPPARDPPARA | |
| Dodecanoate SCHEMBL30380627 | 1.00 | PAOX (0.62) | PAOXGPR84PPARGPPARDPPARA | |
| Arachidic Acid SCHEMBL30379954 | 1.00 | PAOX (0.62) | PAOXGPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL30379986 | 1.00 | PAOX (0.62) | PAOXGPR84PPARGPPARDPPARA | |
| Adipic Acid SCHEMBL28060751 | 1.00 | PAOX (0.62) | PAOXGPR84PPARGPPARDPPARA | |
| Decanoic Acid SCHEMBL29747007 | 0.98 | PAOX (0.61) | PAOXGPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL16027622 | 0.98 | GPR84 (0.63) | PAOXGPR84PPARGPPARDPPARA | |
| SCHEMBL9249058 | 0.96 | GPR84 (0.61) | PAOXGPR84PPARGPPARDPPARA | |
| Heptanoate SCHEMBL16028175 | 0.96 | GPR84 (0.61) | PAOXGPR84PPARGPPARDPPARA | |
| Octanoic Acid SCHEMBL16027973 | 0.96 | GPR84 (0.61) | PAOXGPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482802-A1 | NOVEL PESTICIDE FORMULATIONS | Burnet, Michael (DE) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011040956-A1 | NOVEL PESTICIDE FORMULATIONS | BURNET MICHAEL (DE) | 2011-04-07 | — | — | WO | disclosed |