SCHEMBL16675128

SCHEMBL16675128

c1ccc(-n2c3ccccc3c3ccc4c5cc(-c6ccc7c(c6)c6ccc8c9ccccc9n(-c9ccccc9)c8c6n7-c6nc(-c7ccc(-c8cccc9ccccc89)cc7)c7ccccc7n6)ccc5n(-c5ccccc5)c4c32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 3/20 0.37
HPGD P15428 3/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 4/20 0.36
LMNA P02545 1/20 0.35
ATM Q13315 2/20 0.34
MAPK1 P28482 2/20 0.34
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PTGER4 P35408 1/20 0.34
FLT3 P36888 2/20 0.33
BMX P51813 1/20 0.33
TLR4 O00206 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16404904 0.92 KDM4E (0.40) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL15682518 0.91 KDM4E (0.38) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL17408349 0.90 ALDH1A1 (0.36) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL19979384 0.90 KDM4E (0.36) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL17904191 0.90 KDM4E (0.41) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL16475802 0.89 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21577593 0.88 ALDH1A1 (0.36) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL21168894 0.88 KDM4E (0.36) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL15682593 0.88 ALDH1A1 (0.39) ALDH1A1KDM4EHPGDMAPTNPSR1
SCHEMBL17451697 0.88 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015060684-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-30 WO disclosed