SCHEMBL16675178

SCHEMBL16675178

COC(=O)Oc1ccc(C(=O)Oc2cc(OC(=O)c3ccc(OC(=O)OC)cc3)cc(OC(=O)c3ccc(OC(=O)OC)cc3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.51
ACR P10323 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MEN1 O00255 2/20 0.51
HGFAC Q04756 1/20 0.51
PRSS1 P07477 3/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HSD17B10 Q99714 1/20 0.48
MAPT P10636 3/20 0.47
GFER P55789 1/20 0.47
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PARP10 Q53GL7 1/20 0.47
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17933730 0.89 CA1 (0.66) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL17933390 0.89 CA1 (0.66) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL14407741 0.87 TDP1 (0.60) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL16429581 0.87 CA1 (0.60) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL16429580 0.87 CA1 (0.60) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL11231398 0.86 CA1 (0.67) KMT2AACRMEN1HGFACPRSS1
SCHEMBL10306605 0.83 KMT2A (0.71) KMT2AMEN1LMNACYP1A2MAPT
SCHEMBL15996707 0.82 KMT2A (0.50) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL7518320 0.82 CA1 (0.72) KMT2AACRSMN1; SMN2MEN1HGFAC
SCHEMBL18531380 0.82 ALDH1A1 (0.50) KMT2AACRSMN1; SMN2MEN1HGFAC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed