SCHEMBL16675181

SCHEMBL16675181

O=C(Oc1ccccc1)c1ccc(Oc2cc(Oc3ccc(C(=O)Oc4ccccc4)cc3)cc(Oc3ccc(C(=O)Oc4ccccc4)cc3)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.61
MAPT P10636 6/20 0.56
KMT2A Q03164 5/20 0.56
MEN1 O00255 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
NSD2 O96028 1/20 0.56
SRD5A2 P31213 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
TMPRSS15 P98073 1/20 0.54
ALDH1A1 P00352 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PKM P14618 1/20 0.53
ALOX5 P09917 1/20 0.50
RAB9A P51151 1/20 0.50
AKR1C3 P42330 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9240757 0.94 PARP10 (0.67) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL70401 0.94 PARP10 (0.67) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL8209000 0.94 PARP10 (0.67) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL11149811 0.90 PARP10 (0.67) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL9809043 0.88 PARP10 (0.69) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL9809037 0.88 PARP10 (0.69) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL11208890 0.88 AKR1C3 (0.64) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL8205435 0.86 PARP10 (0.78) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL70034 0.86 PARP10 (0.70) PARP10MAPTKMT2AMEN1TDP1
SCHEMBL8638980 0.86 PARP10 (0.57) PARP10MAPTKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed