SCHEMBL70401

SCHEMBL70401

O=C(Oc1ccccc1)c1ccc(Oc2ccc(C(=O)Oc3ccccc3)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 2/20 0.67
SRD5A2 P31213 3/20 0.60
KMT2A Q03164 4/20 0.59
MEN1 O00255 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
PRSS1 P07477 1/20 0.59
ACR P10323 1/20 0.59
TMPRSS15 P98073 1/20 0.59
MAPT P10636 5/20 0.58
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PKM P14618 1/20 0.58
NSD2 O96028 1/20 0.56
RAB9A P51151 1/20 0.54
HSD17B10 Q99714 1/20 0.53
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209000 1.00 PARP10 (0.67) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL9240757 1.00 PARP10 (0.67) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL11149811 0.96 PARP10 (0.67) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL16675181 0.94 PARP10 (0.61) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL9809037 0.94 PARP10 (0.69) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL9809043 0.94 PARP10 (0.69) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL8205435 0.91 PARP10 (0.78) PARP10KMT2AMEN1SMN1; SMN2PRSS1
SCHEMBL70034 0.91 PARP10 (0.70) PARP10KMT2AMEN1SMN1; SMN2PRSS1
SCHEMBL6032517 0.91 PARP10 (0.57) PARP10SRD5A2KMT2AMEN1SMN1; SMN2
SCHEMBL8638980 0.91 PARP10 (0.57) PARP10SRD5A2KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62234042-A None JP disclosed
JP-62234041-A None JP disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
JP-S62234042-A PRODUCTION OF 4,4'-(P-HYDROXYBENZOYL)DIPHENYL ETHER ASAHI CHEM IND CO LTD 1987-10-14 JP disclosed
JP-S62234041-A PRODUCTION OF 4,4'-(P-HYDROXYBENZOYL)DIPHENYL ETHER ASAHI CHEM IND CO LTD 1987-10-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 PARP10 1526/4885SRD5A2 2593/4885KMT2A 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.