Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.76 |
| ▸ | RAB9A | P51151 | 8/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | HPGD | P15428 | 7/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.73 |
| ▸ | RELA | Q04206 | 1/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13004548 | 0.94 | NPC1 (0.85) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL29121418 | 0.86 | RAB9A (1.00) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL17877090 | 0.85 | NPC1 (0.96) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL27477884 | 0.85 | RAB9A (0.96) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL1251992 | 0.83 | NPC1 (0.71) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL27477057 | 0.83 | NPC1 (0.73) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL2360960 | 0.82 | NPC1 (0.73) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL16407501 | 0.82 | NPC1 (0.90) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL16407493 | 0.82 | NPC1 (0.90) | NPC1RAB9AKMT2AALDH1A1KDM4E | |
| SCHEMBL14169269 | 0.82 | KDM4E (0.76) | NPC1RAB9AKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150114257-A1 | METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY | Konica Minolta, Inc. (JP) | 2015-04-30 | — | — | US | disclosed |
| US-20150114257-A1 | METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY | Konica Minolta, Inc. (JP) | 2015-04-30 | — | — | US | disclosed |