SCHEMBL16675304

SCHEMBL16675304

c1ccc(-n2c3ccccc3c3ccc4c5cc(-c6cccc7c8ccc9c%10ccccc%10n(-c%10ccccc%10)c9c8n(-c8ccccc8)c67)ccc5n(-c5ccccc5)c4c32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 3/20 0.47
ATM Q13315 1/20 0.47
DUSP3 P51452 1/20 0.40
PTGER4 P35408 1/20 0.38
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 2/20 0.34
MAPK8 P45983 1/20 0.34
MAPK9 P45984 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
TSPO P30536 2/20 0.33
NPY5R Q15761 2/20 0.33
MAPK14 Q16539 1/20 0.33
HPGD P15428 2/20 0.32
HDAC4 P56524 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12447553 0.94 L3MBTL1 (0.55) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL15436072 0.93 L3MBTL1 (0.53) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL15436082 0.93 L3MBTL1 (0.53) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL12447554 0.91 L3MBTL1 (0.51) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL18352546 0.91 L3MBTL1 (0.51) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL17229033 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL14296113 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL16901372 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL16901042 0.90 L3MBTL1 (0.50) L3MBTL1KDM4EATMDUSP3PTGER4
SCHEMBL21578616 0.89 L3MBTL1 (0.46) L3MBTL1KDM4EATMDUSP3PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015060684-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-04-30 WO disclosed