Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1065240 | 0.82 | HPGD (0.47) | KMT2AKDM4EALDH1A1PTGS2HPGD | |
| SCHEMBL29315637 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1HPGDGAANPC1 | |
| SCHEMBL4349728 | 0.81 | KMT2A (0.45) | KMT2AKDM4EALDH1A1PTGS2HPGD | |
| SCHEMBL19328339 | 0.81 | KMT2A (0.45) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL3988594 | 0.80 | KMT2A (0.41) | KMT2AALDH1A1PTGS2HPGDNPSR1 | |
| SCHEMBL3990526 | 0.80 | KDM4E (0.41) | KMT2AKDM4EALDH1A1PTGS2HPGD | |
| SCHEMBL3352182 | 0.80 | KMT2A (0.72) | KMT2AALDH1A1HPGDTSHRGAA | |
| SCHEMBL1164883 | 0.78 | KMT2A (0.47) | KMT2AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL392037 | 0.77 | ALDH1A1 (0.44) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL13828022 | 0.77 | MAPT (0.52) | ALDH1A1PTGS2HPGDTSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | HOWARD UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | HOWARD UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-11576901-B2 | Methods for treating viral infection | HOWARD UNIVERSITY (US) | 2023-02-14 | — | — | US | disclosed |
| US-20220211673-A1 | METHODS FOR TREATING AGAINST VIRUSES | HOWARD UNIVERSITY (US) | 2022-07-07 | — | — | US | disclosed |
| US-20220168277-A1 | DRUG INHIBITOR AGAINST MIGRATION AND INVASION OF CANCER CELLS AND METHODS OF TREATING AGAINST METASTASIS OF CANCER CELLS | HOWARD UNIVERSITY (US) | 2022-06-02 | — | — | US | disclosed |
| US-20200297699-A1 | METHODS FOR TREATING VIRAL INFECTION | GEORGETOWN UNIVERSITY | 2020-09-24 | — | — | US | disclosed |
| WO-2017165885-A1 | METHODS FOR TREATING VIRAL INFECTION | ULLAH HEMAYET (US) | 2017-09-28 | — | — | WO | disclosed |
| CN-105001241-A | S-triazolo-thiadiazole and thiadiazine derivatives, preparation method and application thereof | INST MED BIOTECHNOLOGY CAMS | 2015-10-28 | — | — | CN | disclosed |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | RACK1, ROS1, HSF1 | KMT2A 2063/4885KDM4E 2234/4885ALDH1A1 2652/4885 |
| US-20220211673-A1 | METHODS FOR TREATING AGAINST VIRUSES | EIF2AK2, RPL41, EIF4E | KMT2A 3736/4885KDM4E 2842/4885ALDH1A1 4272/4885 |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | RACK1, ROS1, HSF1 | KMT2A 2063/4885KDM4E 2234/4885ALDH1A1 2652/4885 |
| US-11576901-B2 | Methods for treating viral infection | RPL5, RPL35, RPL17 | KMT2A 3563/4885KDM4E 3058/4885ALDH1A1 3078/4885 |
| US-20200297699-A1 | METHODS FOR TREATING VIRAL INFECTION | RPL5, RPL35, RPL17 | KMT2A 3563/4885KDM4E 3058/4885ALDH1A1 3078/4885 |
| US-20220168277-A1 | DRUG INHIBITOR AGAINST MIGRATION AND INVASION OF CANCER CELLS AND METHODS OF TREATING AGAINST METASTASIS OF CANCER CELLS | TUBB1, TTBK1, MKI67 | KMT2A 3100/4885KDM4E 3947/4885ALDH1A1 774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.