Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675468 | 0.83 | TP53 (0.44) | TP53MAPTSMN1; SMN2HTR2AHTR1D | |
| SCHEMBL22643949 | 0.83 | HTR1D (0.49) | TP53MAPTHTR2AHTR1DKIF11 | |
| SCHEMBL31567584 | 0.81 | TP53 (0.50) | TP53MAPTSMN1; SMN2HTR2AHTR1D | |
| SCHEMBL12244348 | 0.81 | TP53 (0.50) | TP53MAPTSMN1; SMN2HTR2AHTR1D | |
| SCHEMBL22643874 | 0.80 | HTR1D (0.48) | TP53MAPTHTR2AHTR1DHTR2C | |
| SCHEMBL20970887 | 0.75 | TP53 (0.46) | TP53MAPTSMN1; SMN2HTR2AHTR1D | |
| SCHEMBL8409476 | 0.75 | HTR2A (0.47) | TP53MAPTSMN1; SMN2HTR2AHTR1D | |
| SCHEMBL6713999 | 0.75 | TP53 (0.46) | TP53MAPTSMN1; SMN2HTR2AHTR1D | |
| SCHEMBL21399387 | 0.75 | TP53 (0.55) | TP53MAPTSMN1; SMN2KIF11 | |
| SCHEMBL1120490 | 0.74 | HTR2A (0.67) | TP53MAPTSMN1; SMN2HTR2AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | HOWARD UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | RACK1, ROS1, HSF1 | TP53 2296/4885MAPT 1846/4885SMN1; SMN2 4793/4885 |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | RACK1, ROS1, HSF1 | TP53 2296/4885MAPT 1846/4885SMN1; SMN2 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.