Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675679 | 1.00 | KMT2A (0.54) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL12047039 | 1.00 | KMT2A (0.54) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL4714490 | 0.94 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL4714492 | 0.94 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL5406078 | 0.83 | BTK (0.58) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL1813191 | 0.81 | KMT2A (0.55) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL3206911 | 0.80 | KMT2A (0.54) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL3206908 | 0.80 | KMT2A (0.54) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL14169340 | 0.79 | ALDH1A1 (0.58) | KMT2AL3MBTL1KDM1AMAOBCTSL | |
| SCHEMBL31520824 | 0.79 | KDM1A (0.57) | KMT2AL3MBTL1KDM1AMAOBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |