Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12367107 | 0.91 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11934694 | 0.85 | MAPT (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL21874744 | 0.82 | MAPT (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL18919642 | 0.82 | MAPT (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16675742 | 0.82 | MEN1 (0.51) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16934915 | 0.81 | MAPT (0.59) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2557104 | 0.80 | NOTUM (0.65) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL24073901 | 0.79 | MAPT (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2259716 | 0.79 | MAPT (0.57) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3440420 | 0.79 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |