Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440420 | 0.92 | MAPT (0.54) | MEN1MAPTKMT2AKDM4EWDR5 | |
| SCHEMBL29833037 | 0.87 | WDR5 (0.43) | MEN1MAPTKMT2AKDM4EWDR5 | |
| SCHEMBL28253934 | 0.85 | MAPT (0.52) | MEN1MAPTKMT2AKDM4EHPN | |
| SCHEMBL25046030 | 0.83 | MAPT (0.53) | MEN1MAPTKMT2AWDR5ALDH1A1 | |
| SCHEMBL4297250 | 0.83 | MAPT (0.53) | MEN1MAPTKMT2AWDR5ALDH1A1 | |
| SCHEMBL12005391 | 0.83 | MAPT (0.53) | MEN1MAPTKMT2AWDR5ALDH1A1 | |
| SCHEMBL16675691 | 0.82 | MAPT (0.55) | MEN1MAPTKMT2AKDM4EHPN | |
| SCHEMBL10127786 | 0.82 | MAPT (0.52) | MEN1MAPTKMT2AKDM4EHTR7 | |
| SCHEMBL328338 | 0.80 | HTR7 (0.50) | MEN1MAPTKMT2AKDM4EHTR7 | |
| SCHEMBL12367107 | 0.79 | MAPT (0.59) | MEN1MAPTKMT2AKDM4EHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |