Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19936629 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4EKDM2BALOX15TSHR | |
| SCHEMBL27363758 | 0.93 | KDM4E (0.35) | ALDH1A1KDM4EKDM2BALOX15TSHR | |
| SCHEMBL24204537 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KDM4EKDM2BALOX15TSHR | |
| SCHEMBL14355437 | 0.91 | — | — | |
| SCHEMBL15089010 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRTDP1USP2 | |
| SCHEMBL15088721 | 0.87 | ALDH1A1 (0.49) | ALDH1A1KDM4ETSHRTDP1USP2 | |
| SCHEMBL736095 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EKDM2BALOX15KMT2A | |
| SCHEMBL1646548 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EKDM2BALOX15KMT2A | |
| SCHEMBL736305 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4EKDM2BALOX15KMT2A | |
| SCHEMBL20080900 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4ETSHRTDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |