Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 3/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 4/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667571 | 1.00 | FEN1 (0.40) | FEN1ERN1MAPK8HSP90AA1HSP90AB1 | |
| SCHEMBL1667570 | 1.00 | FEN1 (0.40) | FEN1ERN1MAPK8HSP90AA1HSP90AB1 | |
| SCHEMBL12797903 | 0.88 | FEN1 (0.34) | FEN1MAPK8HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL1667617 | 0.86 | LMNA (0.34) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1667613 | 0.86 | LMNA (0.34) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1667620 | 0.86 | LMNA (0.34) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1667615 | 0.86 | LMNA (0.34) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1668111 | 0.81 | HSP90AA1 (0.41) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1668112 | 0.81 | HSP90AA1 (0.41) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL1668113 | 0.81 | HSP90AA1 (0.41) | FEN1MAPK8HSP90AA1HSP90AB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |