Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.39 |
| ▸ | CCNH | P51946 | 1/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.37 |
| ▸ | AURKA | O14965 | 4/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675911 | 0.90 | NPC1 (0.39) | NPY5RCCNA2CDK2CCNA1NPC1 | |
| SCHEMBL16682180 | 0.87 | CYP2D6 (0.51) | NPY5RCCNA2CDK2CCNA1NPC1 | |
| SCHEMBL16865705 | 0.85 | CCNA2 (0.50) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL16675898 | 0.83 | NPC1 (0.39) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL16675894 | 0.83 | RAB9A (0.39) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL16865707 | 0.81 | NPC1 (0.47) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL16865704 | 0.80 | RAB9A (0.57) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL16675904 | 0.80 | GRM4 (0.40) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL16675906 | 0.80 | NPC1 (0.36) | CCNA2CDK2CCNA1NPC1RAB9A | |
| SCHEMBL9920888 | 0.79 | NPC1 (0.43) | CCNA2CDK2CCNA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580391-B2 | Saturated acyl guanidine for inhibition of F1F0-ATPase | LYCERA CORPORATION (US) | 2017-02-28 | — | — | US | disclosed |
| US-20150119439-A1 | SATURATED ACYL GUANIDINE FOR INHIBITION OF F1F0-ATPASE | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119439-A1 | SATURATED ACYL GUANIDINE FOR INHIBITION OF F1F0-ATPASE | ATP5F1A, ATP5F1D, ATP5F1C | NPY5R 4621/4885CCNA2 2214/4885CDK2 3048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.