Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078113 | 0.81 | L3MBTL1 (0.53) | L3MBTL1KDM1AMAPTESRRAESR2 | |
| SCHEMBL10095240 | 0.78 | L3MBTL1 (0.53) | L3MBTL1ESRRAESR2 | |
| SCHEMBL10095319 | 0.75 | L3MBTL1 (0.50) | L3MBTL1KDM1AESRRAESR2 | |
| SCHEMBL2285430 | 0.75 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1ESRRAESR2KDM4E | |
| SCHEMBL14466214 | 0.75 | L3MBTL1 (0.50) | L3MBTL1 | |
| SCHEMBL23887014 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4E | |
| SCHEMBL980952 | 0.74 | MAPT (0.53) | L3MBTL1KDM1AALDH1A1MAPTESRRA | |
| SCHEMBL10095338 | 0.74 | MEN1 (0.49) | L3MBTL1ESRRAESR2 | |
| SCHEMBL10095341 | 0.74 | ESRRA (0.51) | L3MBTL1ESRRAESR2 | |
| SCHEMBL30176395 | 0.74 | KDM4E (0.52) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |