Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667678 | 0.88 | FEN1 (0.33) | FEN1APPUSP14ALDH1A1PPARG | |
| SCHEMBL1668112 | 0.82 | HSP90AA1 (0.41) | FEN1USP14KDM4EPPARGMAPK8 | |
| SCHEMBL1668113 | 0.82 | HSP90AA1 (0.41) | FEN1USP14KDM4EPPARGMAPK8 | |
| SCHEMBL1668111 | 0.82 | HSP90AA1 (0.41) | FEN1USP14KDM4EPPARGMAPK8 | |
| SCHEMBL22227504 | 0.81 | HPGD (0.33) | ALDH1A1KDM4EMAPTSMN1; SMN2PPARG | |
| SCHEMBL1077736 | 0.81 | HPGD (0.33) | ALDH1A1KDM4EMAPTSMN1; SMN2PPARG | |
| SCHEMBL1667729 | 0.80 | NTRK1 (0.33) | FEN1APPUSP14PPARG | |
| SCHEMBL1667736 | 0.80 | NTRK1 (0.33) | FEN1APPUSP14PPARG | |
| SCHEMBL1667731 | 0.80 | NTRK1 (0.33) | FEN1APPUSP14PPARG | |
| SCHEMBL12797903 | 0.79 | FEN1 (0.34) | FEN1APPALDH1A1PPARGMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |