SCHEMBL166774

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13077015	0.88	CXCR3 (0.41)	THRBCXCR3KCNH2L3MBTL1MAPT
	SCHEMBL115528	0.83	CXCR3 (0.52)	CXCR3KCNH2L3MBTL1MAPTALDH1A1
	SCHEMBL114668	0.83	CXCR3 (0.41)	CXCR3KCNH2L3MBTL1MAPTPOLB
	SCHEMBL3731245	0.81	GRIN2B (0.41)	CXCR3KCNH2L3MBTL1MAPTKDM4E
	SCHEMBL115433	0.79	MAPT (0.47)	CXCR3KCNH2L3MBTL1MAPTPOLB
	SCHEMBL3730944	0.78	CXCR3 (0.43)	THRBCXCR3KCNH2L3MBTL1MAPT
	SCHEMBL116261	0.78	CXCR3 (0.63)	CXCR3L3MBTL1
	SCHEMBL114806	0.78	CXCR3 (0.44)	CXCR3KCNH2
	SCHEMBL3743174	0.78	MAPT (0.43)	CXCR3KCNH2L3MBTL1MAPTPOLB
	SCHEMBL3730469	0.78	MAPT (0.43)	CXCR3KCNH2L3MBTL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.