Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13277048 | 0.80 | RAB9A (0.47) | RAB9AKCNH2MAOBACHESMPD1 | |
| SCHEMBL11903743 | 0.77 | KCNH2 (0.53) | RAB9AKCNH2MAOBSMPD1MAOA | |
| SCHEMBL11903745 | 0.77 | KCNH2 (0.53) | RAB9AKCNH2MAOBSMPD1MAOA | |
| SCHEMBL13277597 | 0.75 | MAOB (0.48) | RAB9AKCNH2MAOBSMPD1CYP11B1 | |
| SCHEMBL13277598 | 0.75 | MAOB (0.48) | RAB9AKCNH2MAOBSMPD1CYP11B1 | |
| SCHEMBL1670147 | 0.74 | KCNH2 (0.46) | RAB9AKCNH2MAOBSMPD1MMP2 | |
| SCHEMBL1670144 | 0.74 | KCNH2 (0.46) | RAB9AKCNH2MAOBSMPD1MMP2 | |
| SCHEMBL1667537 | 0.73 | MAOB (0.55) | RAB9AKCNH2MAOBMAOA | |
| SCHEMBL1667535 | 0.73 | MAOB (0.55) | RAB9AKCNH2MAOBMAOA | |
| SCHEMBL1667636 | 0.73 | KCNH2 (0.56) | RAB9AKCNH2MAOBSMPD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042217-A1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | ORYZON GENOMICS S.A. (ES) | 2011-04-14 | — | — | WO | disclosed |