Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032754 | 1.00 | RECQL (0.72) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL27158696 | 1.00 | RECQL (0.72) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL2224096 | 1.00 | RECQL (0.72) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL27845521 | 0.90 | TP53 (0.61) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| Levulinic Acid, 3-Benzylidenyl- SCHEMBL4293071 | 0.84 | RECQL (1.00) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL1325523 | 0.84 | RECQL (0.68) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL28654785 | 0.84 | RECQL (0.62) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL28854668 | 0.84 | CYP3A4 (0.59) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL23294031 | 0.82 | RECQL (0.51) | RECQLCYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9045611 | 0.82 | RECQL (0.56) | RECQLCYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107963989-A | A kind of preparation method of Mitiglinide Calcium | 江西济民可信药业有限公司 | 2018-04-27 | — | — | CN | claimed |
| CN-104311471-B | Improved mitiglinide calcium industrialized preparation method | 山东省生物医药科学院 | 2017-05-17 | — | — | CN | claimed |
| EP-2145921-B1 | Vulcanizable polymer compositions | ARLANXEO DEUTSCHLAND GMBH (DE) | 2017-01-25 | — | — | EP | claimed |
| CN-102898348-B | A kind of preparation method of S 21403 | DISHA PHARMACEUTICAL INDUSTRY GROUP CORP., LTD. (CN) | 2015-09-02 | — | — | CN | claimed |
| CN-103450069-B | Preparation method of mitiglinide calcium | UNIV SHANXI DATONG | 2015-04-15 | — | — | CN | claimed |
| CN-104311471-A | Improved mitiglinide calcium industrialized preparation method | SHANDONG ACADEMY OF PHARMACEUTICAL SCIENCES | 2015-01-28 | — | — | CN | claimed |
| EP-2199326-B1 | Vulcanizable polymer compositions | LANXESS DEUTSCHLAND GMBH (DE) | 2014-10-29 | — | — | EP | claimed |
| CN-103450069-A | Preparation method of mitiglinide calcium | UNIV SHANXI DATONG | 2013-12-18 | — | — | CN | claimed |
| CN-102898348-A | Preparation method for Mitiglinide calcium | DISHA PHARMACEUTICAL GROUP CO | 2013-01-30 | — | — | CN | claimed |
| CN-101973926-B | Method for preparing R-mitiglinide calcium | WEIHAI DISU PHARMACEUTICAL CO LTD | 2012-09-19 | — | — | CN | claimed |
| CN-102659561-A | Method for preparing S-benzylsuccinic acid | SHANDONG BOYUAN PHARMACEUTICAL CO LTD | 2012-09-12 | — | — | CN | claimed |
| WO-2011085445-A1 | FLOTATION REAGENTS | TEEBEE HOLDINGS PTY LTD (AU) | 2011-07-21 | — | — | WO | claimed |
| CN-102101838-A | Preparation method of mitiglinide calcium | ZHANGJIAGANG TIANYOU NEW MATERIAL TECHNOLOGY CO LTD | 2011-06-22 | — | — | CN | claimed |
| CN-101973926-A | Method for preparing R-mitiglinide calcium | WEIHAI DISU PHARMACEUTICAL CO LTD | 2011-02-16 | — | — | CN | claimed |
| CN-1830961-A | Medicine synthesis process for treating diabetes and application of medicine preparation | ZHENG SHICAI (CN) | 2006-09-13 | — | — | CN | claimed |
| EP-0512415-B1 | Process for the enantioselective synthesis of 2(R)-benzyl succanamide derivatives | HOECHST AG (DE) | 1997-08-06 | — | — | EP | claimed |
| US-5321139-A | Amination of phenylitaconic anhydride, catalytic reduction of formed amide; renin inhibitor | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-14 | — | — | US | claimed |
| CN-118576791-A | Anticoagulation coating and preparation method thereof | 四川大学华西医院 | 2024-09-03 | — | — | CN | disclosed |
| US-4086338-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4052511-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-04 | — | — | US | disclosed |