SCHEMBL1667802

SCHEMBL1667802

CCCCCCCCC(=O)O[C@H]1CC[C@@]2(C)C(=CCC3C2CC[C@@]2(C)C3CC[C@@H]2[C@H](C)CCCC(C)C)C1

nearest known ligand 0.84

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.70
CYP46A1 Q9Y6A2 2/20 0.69
USP2 O75604 2/20 0.65
LMNA P02545 1/20 0.65
ABCB1 P08183 1/20 0.65
OSBP P22059 1/20 0.65
RORC P51449 1/20 0.65
OSBP2 Q969R2 1/20 0.65
PLA2G2A P14555 1/20 0.62
NPC1 O15118 1/20 0.59
NR1H3 Q13133 2/20 0.58
NPC1L1 Q9UHC9 1/20 0.58
GBA1 P04062 2/20 0.58
UGCG Q16739 2/20 0.58
GBA2 Q9HCG7 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL161427 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL4624683 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL19919940 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL17639910 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL22620094 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL21177689 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL126915 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL161428 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL18310374 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL1697148 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10376891-B2 System and method for temperature referencing for melt curve data collection CANON U.S. LIFE SCIENCES, INC. (US) 2019-08-13 US disclosed
US-20160325285-A1 SYSTEM AND METHOD FOR TEMPERATURE REFERENCING FOR MELT CURVE DATA COLLECTION CANON U.S. LIFE SCIENCES, INC. (US) 2016-11-10 US disclosed
US-9393566-B2 System and method for temperature referencing for melt curve data collection CANON U.S. LIFE SCIENCES, INC. (US) 2016-07-19 US disclosed
EP-2960226-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2015-12-30 EP disclosed
WO-2015129540-A1 LIQUID CRYSTAL COMPOUND HAVING 1,1,3,3-TETRAFLUOROALLYLOXY GROUP, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC株式会社 2015-09-03 WO disclosed
EP-2313485-B1 SYSTEM AND METHOD FOR TEMPERATURE REFERENCING FOR MELT CURVE DATA COLLECTION CANON US LIFE SCIENCES INC (US) 2015-08-05 EP disclosed
WO-2013065622-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC株式会社 (JP) 2013-05-10 WO disclosed
EP-2313485-A2 SYSTEM AND METHOD FOR TEMPERATURE REFERENCING FOR MELT CURVE DATA COLLECTION Canon U.S. Life Sciences, Inc. (US) 2011-04-27 EP disclosed
WO-2009158304-A2 SYSTEM AND METHOD FOR TEMPERATURE REFERENCING FOR MELT CURVE DATA COLLECTION CANON U.S. LIFE SCIENCES, INC. (US) 2009-12-30 WO disclosed