SCHEMBL161427

SCHEMBL161427

CCCCCCCCCC(=O)O[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1

nearest known ligand 0.84

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.70
CYP46A1 Q9Y6A2 2/20 0.69
USP2 O75604 2/20 0.65
LMNA P02545 1/20 0.65
ABCB1 P08183 1/20 0.65
OSBP P22059 1/20 0.65
RORC P51449 1/20 0.65
OSBP2 Q969R2 1/20 0.65
PLA2G2A P14555 1/20 0.62
NPC1 O15118 1/20 0.59
NR1H3 Q13133 2/20 0.58
NPC1L1 Q9UHC9 1/20 0.58
GBA1 P04062 2/20 0.58
UGCG Q16739 2/20 0.58
GBA2 Q9HCG7 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4624683 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL19919940 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL17639910 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL22620094 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL21177689 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL126915 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL161428 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL1667802 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL18310374 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL1697148 1.00 POLA1 (0.70) POLA1CYP46A1USP2LMNAABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062716-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS POPVAX PRIVATE LTD (IN) 2026-03-05 US claimed
EP-4577196-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS Popvax Private Limited (IN) 2025-07-02 EP claimed
CN-119959397-A Method for simultaneously detecting multiple cholesteric liquid crystal monomers in environmental medium 暨南大学 2025-05-09 CN claimed
WO-2025052180-A2 LIPIDS AND LIPID NANOPARTICLES Axelyf ehf. (IS) 2025-03-13 WO claimed
WO-2024044178-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS POPVAX PRIVATE LIMITED (IN) 2024-02-29 WO claimed
CN-115461096-A Polymer encapsulated drug particles 吉益医疗公司 2022-12-09 CN claimed
EP-4025660-A1 THERMOCHROMIC LIQUID CRYSTAL INKS AND COATINGS Sun Chemical Corporation (US) 2022-07-13 EP claimed
CN-113429775-A UV (ultraviolet) photocuring liquid crystal structure color film and preparation method thereof 广东壮丽彩印股份有限公司 2021-09-24 CN claimed
CN-113248641-A Variable-temperature anti-counterfeiting material based on structural color and preparation method and application thereof 广东壮丽彩印股份有限公司 2021-08-13 CN claimed
CN-108815134-B Preparation and application of biological camouflage targeted nano drug delivery system for treating ischemic stroke 中国药科大学 2021-07-13 CN claimed
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents L'OREAL S.A. (FR) 2006-06-01 US claimed
EP-1647259-A1 use for treatment of keratinic materials of compositions comprising electrophilic monomers and agents forming liquid crystals L'OREAL (FR) 2006-04-19 EP claimed
EP-1328190-B1 TEMPERATURE MEASURING BALLOON BOSTON SCIENT LTD (BB) 2004-12-29 EP claimed
JP-2004510480-A 2004-04-08 JP claimed
EP-1328190-A2 TEMPERATURE MEASURING BALLOON Boston Scientific Limited (BB) 2003-07-23 EP claimed
US-6450971-B1 Temperature measuring balloon SCIMED LIFE SYSTEMS, INC. 2002-09-17 US claimed
WO-2002028276-A2 TEMPERATURE MEASURING BALLOON SCIMED LIFE SYSTEMS, INC. (US) 2002-04-11 WO claimed
US-6328910-B1 FOR IN SITU FORMATION OF AN POLYMERIC CYANOACRYLATE FILM ON MAMMALIAN SKIN WHICH CAN BE USED TO MONITOR THE SURFACE SKIN TEMPERATURE OF MAMMAL MEDLOGIC GLOBAL CORPORATION 2001-12-11 US claimed
US-4097776-A Coated electroluminescent phosphors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1978-06-27 US claimed
US-4066567-A LIQUID CRYSTAL CUMULATIVE DOSIMETER TEMPLE UNIVERSITY (US) 1978-01-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents KRT18, PRKDC, CUTA POLA1 1396/4885CYP46A1 3561/4885USP2 2505/4885
US-20260062716-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS CETP, PLTP, LDLR POLA1 825/4885CYP46A1 476/4885USP2 3448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.