SCHEMBL16680278

SCHEMBL16680278

CC(Cl)C(Cl)(c1ccccc1)S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
LMNA P02545 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
ALDH1A1 P00352 1/20 0.39
POLB P06746 1/20 0.39
PMP22 Q01453 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP2D6 P10635 3/20 0.38
TSHR P16473 2/20 0.37
PTPN1 P18031 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MITF O75030 2/20 0.36
MAPK1 P28482 1/20 0.35
GRIN2D O15399 2/20 0.34
GRIN1 Q05586 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16680334 0.85 CYP1A2 (0.42) CYP1A2LMNAKMT2AMAPTHPGD
SCHEMBL16680108 0.81 CYP1A2 (0.36) CYP1A2CYP2D6TSHRPTPN1MAPK1
SCHEMBL16679565 0.72 CYP1A2 (0.41) CYP1A2LMNAKMT2AMAPTHPGD
SCHEMBL8775959 0.71 CYP1A2 (0.48) CYP1A2LMNAKMT2AMAPTHPGD
SCHEMBL28693125 0.71 CYP2D6 (0.50) CYP1A2LMNAKMT2AMAPTHPGD
SCHEMBL11814116 0.70 TSHR (0.44) CYP1A2KDM4EALDH1A1CYP2D6TSHR
SCHEMBL18634215 0.69 CYP2D6 (0.44) CYP1A2LMNAKMT2AMAPTHPGD
SCHEMBL16680333 0.69 CYP1A2 (0.42) CYP1A2LMNAKMT2AMAPTHPGD
SCHEMBL6049970 0.69 TSHR (0.48) CYP1A2LMNAKDM4EALDH1A1CYP2D6
SCHEMBL16680352 0.68 CYP1A2 (0.45) CYP1A2KMT2AMAPTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10683244-B2 Method for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2020-06-16 US disclosed
US-20190023627-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2019-01-24 US disclosed
US-10106472-B2 Compositions for controlling plant parasitic nematodes and methods for using same YAMASHITA THOMAS T (US) 2018-10-23 US disclosed
US-20170226024-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2017-08-10 US disclosed
US-9661857-B2 Compositions for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2017-05-30 US disclosed
EP-2984060-A1 COMPOSITIONS FOR CONTROLLING PLANT PARASITIC NEMATODES AND METHODS FOR USING SAME Yamashita, Thomas T. (US) 2016-02-17 EP disclosed
US-20150125435-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2015-05-07 US disclosed
WO-2015065581-A1 COMPOSITIONS FOR CONTROLLING PLANT PARASITIC NEMATODES AND METHODS FOR USING SAME YAMASHITA THOMAS T (US) 2015-05-07 WO disclosed