SCHEMBL16680334

SCHEMBL16680334

O=S(=O)(O)C(Cl)(c1ccccc1)C(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
TSHR P16473 3/20 0.39
PTPN1 P18031 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
SRC P12931 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KMT2A Q03164 3/20 0.33
CYP2D6 P10635 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 2/20 0.33
HPGD P15428 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16680278 0.85 CYP1A2 (0.39) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL16680108 0.80 CYP1A2 (0.36) CYP1A2TSHRPTPN1CYP2D6MAPK1
SCHEMBL8775959 0.74 CYP1A2 (0.48) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL16680333 0.72 CYP1A2 (0.42) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL8375533 0.71 CYP1A2 (0.45) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL16680354 0.71 CYP1A2 (0.45) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL16680352 0.71 CYP1A2 (0.45) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL11758958 0.71 PTPN1 (0.38) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL8376961 0.69 CYP1A2 (0.43) CYP1A2TSHRPTPN1SMN1; SMN2CA1
SCHEMBL11715142 0.69 CYP1A2 (0.54) CYP1A2TSHRPTPN1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10683244-B2 Method for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2020-06-16 US disclosed
US-20190023627-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2019-01-24 US disclosed
US-10106472-B2 Compositions for controlling plant parasitic nematodes and methods for using same YAMASHITA THOMAS T (US) 2018-10-23 US disclosed
US-20170226024-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2017-08-10 US disclosed
US-9661857-B2 Compositions for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2017-05-30 US disclosed
EP-2984060-A1 COMPOSITIONS FOR CONTROLLING PLANT PARASITIC NEMATODES AND METHODS FOR USING SAME Yamashita, Thomas T. (US) 2016-02-17 EP disclosed
US-20150125435-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2015-05-07 US disclosed
WO-2015065581-A1 COMPOSITIONS FOR CONTROLLING PLANT PARASITIC NEMATODES AND METHODS FOR USING SAME YAMASHITA THOMAS T (US) 2015-05-07 WO disclosed