SCHEMBL16680396

SCHEMBL16680396

Cc1ccc(S[C@@H]2O[C@@H]3COC(c4ccccc4)O[C@H]3[C@H](OCc3ccccc3)[C@H]2OC(=O)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
SELP P16109 1/20 0.37
BCHE P06276 7/20 0.34
LGALS9 O00182 2/20 0.34
LGALS1 P09382 2/20 0.34
LGALS3 P17931 2/20 0.34
NT5E P21589 1/20 0.33
LGALS7; LGALS7B P47929 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TACR2 P21452 1/20 0.31
GPBAR1 Q8TDU6 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24086080 0.95 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1SELPBCHE
SCHEMBL24086064 0.95 L3MBTL1 (0.49) L3MBTL1KMT2AMEN1SELPBCHE
SCHEMBL7154481 0.91 L3MBTL1 (0.45) L3MBTL1KMT2AMEN1BCHELGALS9
SCHEMBL7154294 0.89 L3MBTL1 (0.51) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL25031785 0.89 L3MBTL1 (0.51) L3MBTL1KMT2AMEN1SELPALDH1A1
SCHEMBL16731453 0.89 L3MBTL1 (0.40) L3MBTL1KMT2AMEN1SELPBCHE
SCHEMBL7145164 0.88 L3MBTL1 (0.50) L3MBTL1KMT2AMEN1SELPBCHE
SCHEMBL7151724 0.88 L3MBTL1 (0.41) L3MBTL1KMT2AMEN1SELPBCHE
SCHEMBL26492359 0.87 L3MBTL1 (0.50) L3MBTL1KMT2AMEN1SELPBCHE
SCHEMBL7151504 0.86 L3MBTL1 (0.40) L3MBTL1KMT2AMEN1BCHELGALS9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344513-A9 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX ACADEMIA SINICA (TW) 2015-12-03 US disclosed
US-20150126721-A1 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX ACADEMIA SINICA (TW) 2015-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344513-A9 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX F2, TBXA2R, PROC L3MBTL1 4460/4885KMT2A 2445/4885MEN1 1419/4885
US-20150126721-A1 METHODS AND INTERMEDIATES FOR THE PREPARATION OF FONDAPARINUX F2, TBXA2R, PROC L3MBTL1 4460/4885KMT2A 2445/4885MEN1 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.