Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16670531 | 0.84 | POLB (0.51) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16670530 | 0.84 | POLB (0.51) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL19969191 | 0.82 | FPR2 (0.59) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL18180166 | 0.82 | FPR2 (0.59) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16670307 | 0.82 | FPR2 (0.45) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16670305 | 0.82 | FPR2 (0.45) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16669962 | 0.82 | FPR2 (0.45) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16670198 | 0.82 | FPR2 (0.45) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16669787 | 0.82 | FPR2 (0.45) | FPR2KMT2AALDH1A1ALOX15MMP9 | |
| SCHEMBL16669963 | 0.82 | FPR2 (0.45) | FPR2KMT2AALDH1A1ALOX15MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015061518-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |