Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 7/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671059 | 0.84 | DDR1 (0.38) | DDR1EPHX2SLC6A3NR1H4PTGES | |
| SCHEMBL16671060 | 0.84 | DDR1 (0.38) | DDR1EPHX2SLC6A3NR1H4PTGES | |
| SCHEMBL16671833 | 0.78 | DPP4 (0.38) | EPHX2NR1H4PTGES | |
| SCHEMBL16671832 | 0.78 | DPP4 (0.38) | EPHX2NR1H4PTGES | |
| SCHEMBL16670731 | 0.76 | DPP4 (0.39) | EPHX2NR1H4PTGES | |
| SCHEMBL16670728 | 0.76 | DPP4 (0.39) | EPHX2NR1H4PTGES | |
| SCHEMBL16682136 | 0.74 | CYP1A1 (0.46) | EPHX2NR1H4 | |
| SCHEMBL16682194 | 0.74 | ALOX5 (0.40) | EPHX2NR1H4PTGES | |
| SCHEMBL16671628 | 0.74 | ALOX5 (0.40) | EPHX2NR1H4PTGES | |
| SCHEMBL16670998 | 0.70 | CA1 (0.39) | EPHX2NR1H4PTGESCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015059618-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-30 | — | — | WO | disclosed |