Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199611 | 0.85 | — | — | |
| SCHEMBL12039716 | 0.83 | TSHR (0.42) | TSHRALDH1A1MAPK1CACNA2D1CACNB3 | |
| SCHEMBL15158732 | 0.82 | TSHR (0.53) | TSHRALDH1A1MAPK1CACNA2D1CACNB3 | |
| SCHEMBL18231993 | 0.81 | TSHR (0.48) | TSHRALDH1A1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL27465229 | 0.81 | ALDH1A1 (0.37) | TSHRALDH1A1MAPK1ALOX15CACNA2D1 | |
| SCHEMBL12059090 | 0.81 | TSHR (0.48) | TSHRALDH1A1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL19428361 | 0.81 | TSHR (0.48) | TSHRALDH1A1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL14646731 | 0.79 | TSHR (0.40) | TSHRALDH1A1MAPK1ALOX15CACNA2D1 | |
| SCHEMBL27831068 | 0.79 | CACNA2D1 (0.50) | TSHRALDH1A1MAPK1ALOX15CACNA2D1 | |
| SCHEMBL7367890 | 0.79 | CACNA2D1 (0.50) | TSHRALDH1A1MAPK1ALOX15CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | claimed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | claimed |
| US-9096622-B2 | Method of producing an aminoalkylalkoxysilane | DOW CORNING CORPORATION (US) | 2015-08-04 | — | — | US | disclosed |
| EP-2488538-B1 | METHOD OF PRODUCING AN AMINOALKYLALKOXYSILANE | DOW CORNING (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2488538-A1 | METHOD OF PRODUCING AN AMINOALKYLALKOXYSILANE | Dow Corning Corporation (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20120190876-A1 | Method Of Producing An Aminoalkylalkoxysilane | DOW SILICONES CORPORATION | 2012-07-26 | — | — | US | disclosed |
| CN-102596972-A | Method of producing an aminoalkylalkoxysilane | DOW CORNING | 2012-07-18 | — | — | CN | disclosed |
| WO-2011046791-A1 | METHOD OF PRODUCING AN AMINOALKYLALKOXYSILANE | DOW CORNING CORPORATION (US) | 2011-04-21 | — | — | WO | disclosed |
| CN-1219953-A | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | disclosed |
| CN-1195369-A | Concentrated and stable fabric softening compositions | PROCTER & GAMBLE (US) | 1998-10-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190876-A1 | Method Of Producing An Aminoalkylalkoxysilane | ASNS, AGPS, HACL2 | TSHR 1773/4885ALDH1A1 3017/4885MAPK1 3883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.