Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 9/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931225 | 0.96 | CA1 (0.37) | CA1CA2TRPV4SLC22A12 | |
| SCHEMBL14931332 | 0.89 | SLC22A12 (0.33) | CA1CA2TRPV4SLC22A12 | |
| SCHEMBL12979525 | 0.86 | EGLN1 (0.32) | CA1CA2TRPV4SLC22A12 | |
| SCHEMBL14943083 | 0.85 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL3480751 | 0.84 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL3480039 | 0.84 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14931259 | 0.84 | TRPV4 (0.34) | TRPV4SLC22A12 | |
| SCHEMBL14943073 | 0.83 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL13032060 | 0.82 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL13031985 | 0.81 | TRPV4 (0.36) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-B1 | NOVEL INHIBITORS OF BETA-LACTAMASE | METHYLGENE INC (CA) | 2015-04-29 | — | — | EP | disclosed |