Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647594 | 0.91 | TDP1 (0.71) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL2487414 | 0.91 | TDP1 (0.71) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL11648754 | 0.88 | TDP1 (0.62) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL11648752 | 0.88 | TDP1 (0.62) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL29848589 | 0.88 | TDP1 (0.62) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL9818179 | 0.86 | TDP1 (0.71) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL9818181 | 0.86 | TDP1 (0.71) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL11411728 | 0.84 | TDP1 (0.59) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL10598727 | 0.84 | CYP3A4 (0.59) | NPC1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL10598728 | 0.84 | CYP3A4 (0.59) | NPC1RAB9AMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108273478-A | A kind of formaldehyde removing composition and product | 李怀玉 | 2018-07-13 | — | — | CN | disclosed |
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | CARL ZEISS MEDITEC AG (DE) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | UACA, ICAM1, VIM | NPC1 4214/4885RAB9A 3139/4885MAPT 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.