Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.58 |
| ▸ | TK2 | O00142 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665230 | 0.87 | TK1 (0.63) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10231090 | 0.87 | TK1 (0.63) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1665228 | 0.87 | TK1 (0.63) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10178250 | 0.87 | TK1 (0.63) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL4426730 | 0.86 | TK1 (0.52) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL15483803 | 0.85 | TK1 (0.61) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL17669967 | 0.85 | TK1 (0.63) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1665347 | 0.83 | TK1 (0.61) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL14680065 | 0.83 | TK1 (0.61) | TK1TK2LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1665352 | 0.83 | TK1 (0.61) | TK1TK2LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |