Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666728 | 0.87 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL16684444 | 0.87 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL16684382 | 0.85 | HSD11B1 (0.71) | HSD11B1 | |
| SCHEMBL16684446 | 0.81 | HSD11B1 (0.66) | HSD11B1 | |
| SCHEMBL16940752 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16666482 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16684423 | 0.79 | HSD11B1 (0.89) | HSD11B1 | |
| SCHEMBL16940724 | 0.79 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16940753 | 0.79 | HSD11B1 (0.75) | HSD11B1 | |
| SCHEMBL16666659 | 0.79 | HSD11B1 (0.75) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865664-A1 | NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | BAMICHEM CO., LTD (KR) | 2015-04-29 | — | — | EP | disclosed |