Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666449 | 1.00 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16684461 | 0.92 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16940701 | 0.82 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16666233 | 0.81 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL16666954 | 0.80 | HSD11B1 (0.74) | HSD11B1 | |
| SCHEMBL2018797 | 0.79 | HSD11B1 (0.65) | HSD11B1 | |
| SCHEMBL16684439 | 0.78 | HSD11B1 (0.74) | HSD11B1 | |
| SCHEMBL16666467 | 0.77 | HSD11B1 (0.73) | HSD11B1 | |
| SCHEMBL14680675 | 0.77 | HSD11B1 (0.91) | HSD11B1 | |
| SCHEMBL16666230 | 0.76 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865664-A1 | NOVEL COMPOUND HAVING ABILITY TO INHIBIT 11B-HSD1 ENZYME OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | BAMICHEM CO., LTD (KR) | 2015-04-29 | — | — | EP | disclosed |