SCHEMBL16685294

SCHEMBL16685294

C=Cc1ccc(F)cc1F.C=Cc1ccccc1F

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 11/20 0.71
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
HTR2A P28223 2/20 0.41
HTR2C P28335 2/20 0.41
KCNH2 Q12809 1/20 0.41
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29413981 0.89 NFE2L2 (0.54) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL319771 0.89 NFE2L2 (0.54) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL50061 0.85
SCHEMBL29906330 0.85
SCHEMBL20995874 0.83 NFE2L2 (1.00) NFE2L2HTR2AHTR2CKCNH2
SCHEMBL20995872 0.83 NFE2L2 (1.00) NFE2L2HTR2AHTR2CKCNH2
Methane SCHEMBL11859929 0.83 NFE2L2 (0.59) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
Water SCHEMBL27875439 0.83 NFE2L2 (0.59) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
Ethylene SCHEMBL28761744 0.83 NFE2L2 (0.59) NFE2L2GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19154062 0.77 NFE2L2 (0.47) NFE2L2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3066166-A1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS Lubrizol Advanced Materials, Inc. (US) 2016-09-14 EP disclosed
WO-2015066163-A1 ACRYLIC DISPERSANTS WITH FUSED AROMATIC IMIDE ANCHOR GROUPS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-05-07 WO disclosed