Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Alanine SCHEMBL16681922 | 1.00 | SLC7A5 (0.46) | SLC7A5LAP3ANPEPTP53GRIN2D | |
| Alanine SCHEMBL16685332 | 1.00 | SLC7A5 (0.46) | SLC7A5LAP3ANPEPTP53GRIN2D | |
| Alanine SCHEMBL11707090 | 0.91 | SLC7A5 (0.48) | SLC7A5LAP3ANPEPTP53 | |
| D-Alanine SCHEMBL28444494 | 0.91 | SLC7A5 (0.48) | SLC7A5LAP3ANPEPTP53 | |
| Alanine SCHEMBL11707081 | 0.91 | SLC7A5 (0.48) | SLC7A5LAP3ANPEPTP53 | |
| Alanine SCHEMBL14764702 | 0.84 | SLC7A5 (0.59) | SLC7A5TP53 | |
| D-Alanine SCHEMBL2027760 | 0.84 | SLC7A5 (0.59) | SLC7A5TP53 | |
| D-Alanine SCHEMBL614024 | 0.84 | SLC7A5 (0.59) | SLC7A5TP53 | |
| Alanine SCHEMBL1332110 | 0.84 | — | — | |
| Alanine SCHEMBL31 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063165-A1 | D-ALANINE PHOSPHORAMIDATE PRONUCLEOTIDES OF 2'-METHYL 2'-FLUORO GUANOSINE NUCLEOSIDE COMPOUNDS FOR THE TREATMENT OF HCV | Idenix Pharmaceuticals LLC (US) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015066370-A1 | D-ALANINE PHOSPHORAMIDATE PRONUCLEOTIDES OF 2'-METHYL 2'-FLUORO GUANOSINE NUCLEOSIDE COMPOUNDS FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |