Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL16685626 | 0.83 | LMNA (0.44) | TSHRKMT2AMEN1CYP2D6POLB | |
| SCHEMBL515589 | 0.82 | CYP2D6 (0.40) | KMT2AMEN1CYP2D6POLBLMNA | |
| SCHEMBL16685629 | 0.81 | LMNA (0.39) | TSHRKMT2AMEN1CYP2D6POLB | |
| SCHEMBL10366921 | 0.77 | TSHR (0.50) | TP53TSHRKMT2AMEN1CYP2D6 | |
| SCHEMBL20584667 | 0.72 | TP53 (0.67) | TP53TSHRRECQLKMT2AMEN1 | |
| SCHEMBL20584666 | 0.72 | TP53 (0.67) | TP53TSHRRECQLKMT2AMEN1 | |
| Hydroxyamine SCHEMBL11026952 | 0.72 | TSHR (0.92) | TP53TSHRRECQLKMT2AMEN1 | |
| Methyl Alcohol SCHEMBL29466887 | 0.72 | TSHR (0.92) | TP53TSHRRECQLKMT2AMEN1 | |
| SCHEMBL11886503 | 0.71 | TSHR (1.00) | TP53TSHRRECQLKMT2ACYP2D6 | |
| SCHEMBL14117921 | 0.71 | TSHR (1.00) | TP53TSHRRECQLKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015063795-A2 | NOVEL PROCESS FOR PREPARATION OF OPTICALLY PURE NOREPHEDRINE AND ITS DERIVATIVES | LAURUS LABS PRIVATE LIMITED (IN) | 2015-05-07 | — | — | WO | disclosed |