Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898390 | 0.88 | TRPV1 (0.52) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL29510910 | 0.84 | NPC1 (0.78) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL26630402 | 0.82 | NPC1 (0.55) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL31036105 | 0.81 | NOTUM (0.61) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL4922780 | 0.81 | MAOB (0.59) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL16406932 | 0.80 | NOTUM (0.54) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL19662760 | 0.80 | NPC1 (0.64) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL4048302 | 0.78 | HTR2A (0.55) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL30279147 | 0.78 | CDC7 (0.55) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL8311439 | 0.78 | CDC7 (0.55) | NPC1ALDH1A1MAPTHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |