SCHEMBL16686237

SCHEMBL16686237

O=C1OC(CI)CN1c1ccc(Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 14/20 0.50
F10 P00742 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16686236 1.00 GRM2 (0.50) GRM2F10
SCHEMBL28922857 0.84 GRM2 (0.63) GRM2F10
SCHEMBL28922766 0.84 GRM2 (0.63) GRM2F10
SCHEMBL16685880 0.84 MAOA (0.58) GRM2
SCHEMBL9823520 0.84 F10 (0.63) GRM2F10
SCHEMBL412168 0.84 MAOA (0.58) GRM2
SCHEMBL28922749 0.84 GRM2 (0.69) GRM2
Hydrochloric Acid SCHEMBL9823521 0.83 F10 (0.61) GRM2F10
SCHEMBL14580024 0.83 F10 (0.53) GRM2F10
SCHEMBL16686252 0.81 MAOA (0.49) GRM2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015066413-A1 OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS NOVARTIS AG (CH) 2015-05-07 WO disclosed