Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 13/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16686252 | 1.00 | MAOA (0.49) | MAOAMAOBPOLBGRM2TSHR | |
| SCHEMBL851157 | 0.86 | MAOA (0.66) | MAOAMAOBPOLBGRM2TSHR | |
| SCHEMBL851156 | 0.86 | MAOA (0.66) | MAOAMAOBPOLBGRM2TSHR | |
| SCHEMBL16686245 | 0.85 | CALML3 (0.50) | MAOAMAOBGRM2F10 | |
| SCHEMBL16686244 | 0.85 | CALML3 (0.50) | MAOAMAOBGRM2F10 | |
| SCHEMBL16686066 | 0.85 | GRM2 (0.44) | MAOAMAOBGRM2F10 | |
| SCHEMBL16686064 | 0.85 | GRM2 (0.44) | MAOAMAOBGRM2F10 | |
| SCHEMBL13232258 | 0.84 | MAOB (0.47) | MAOAMAOBPOLBGRM2TSHR | |
| SCHEMBL1222866 | 0.82 | CALML3 (0.52) | MAOAMAOBGRM2 | |
| SCHEMBL1222864 | 0.82 | CALML3 (0.52) | MAOAMAOBGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |