SCHEMBL16686906

SCHEMBL16686906

O=c1c2ccc3oc4ccccc4c4c(Oc5ccccc5)cc(c2c34)c2nc3ccccc3n12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.47
▸ MAPT P10636 5/20 0.47
▸ CYP1A2 P05177 3/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ CAMKK1 Q8N5S9 2/20 0.47
▸ CAMKK2 Q96RR4 2/20 0.47
▸ CYP2C9 P11712 2/20 0.47
▸ CYP2C19 P33261 2/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CASP1 P29466 1/20 0.47
▸ CASP7 P55210 1/20 0.47
▸ BCL2 P10415 1/20 0.45
▸ CSNK2A2 P19784 1/20 0.45
▸ CSNK2B P67870 1/20 0.45
▸ CSNK2A1 P68400 1/20 0.45
▸ PIM3 Q86V86 1/20 0.45
▸ DYRK2 Q92630 1/20 0.45
▸ MKNK1 Q9BUB5 1/20 0.45
▸ PIM2 Q9P1W9 1/20 0.45
▸ NPC1 O15118 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18045732 0.96 KMT2A (0.47) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL16687010 0.89 KMT2A (0.41) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL16686884 0.89 KMT2A (0.41) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL16686870 0.87 BCL2 (0.42) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL22142653 0.86 KMT2A (0.52) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL22351891 0.86 KMT2A (0.52) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL16686852 0.84 BCL2 (0.42) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL13478129 0.83 KMT2A (0.47) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL13478128 0.83 KMT2A (0.47) KMT2AMAPTCYP1A2MEN1CAMKK1
SCHEMBL16686901 0.80 BCL2 (0.58) KMT2AMAPTCYP1A2MEN1CAMKK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10329482-B2 Class of organic phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting SIGNIFY HOLDING B.V. (NL) 2019-06-25 — — US claimed
EP-3063249-B1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING SIGNIFY HOLDING BV (NL) 2019-04-17 — — EP claimed
EP-3209747-B1 NEW CLASS OF ORGANIC PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING PHILIPS LIGHTING HOLDING BV (NL) 2018-12-12 — — EP claimed
EP-3209747-A1 NEW CLASS OF ORGANIC PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING Philips Lighting Holding B.V. (NL) 2017-08-30 — — EP claimed
US-9676998-B2 Class of green/yellow emitting phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting PHILIPS LIGHTING HOLDING B.V. (NL) 2017-06-13 — — US claimed
US-20160264860-A1 CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING SIGNIFY HOLDING B.V. (NL) 2016-09-15 — — US claimed
US-10329482-B2 Class of organic phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting SIGNIFY HOLDING B.V. (NL) 2019-06-25 — — US disclosed
EP-3063249-B1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING SIGNIFY HOLDING BV (NL) 2019-04-17 — — EP disclosed
EP-3209747-B1 NEW CLASS OF ORGANIC PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING PHILIPS LIGHTING HOLDING BV (NL) 2018-12-12 — — EP disclosed
US-20180016491-A1 NEW CLASS OF ORGANIC PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING PHILIPS LIGHTING HOLDING B.V. (NL) 2018-01-18 — — US disclosed
EP-3209747-A1 NEW CLASS OF ORGANIC PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING Philips Lighting Holding B.V. (NL) 2017-08-30 — — EP disclosed
US-9676998-B2 Class of green/yellow emitting phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting PHILIPS LIGHTING HOLDING B.V. (NL) 2017-06-13 — — US disclosed
US-20160264860-A1 CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING SIGNIFY HOLDING B.V. (NL) 2016-09-15 — — US disclosed
EP-3063249-A1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING Philips Lighting Holding B.V. (NL) 2016-09-07 — — EP disclosed
WO-2015062916-A1 NEW CLASS OF GREEN/YELLOW EMITTING PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING KONINKLIJKE PHILIPS N.V. (NL) 2015-05-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10329482-B2 Class of organic phosphors based on derivatives of benzimidazoxanthenoisoquinolinone for LED lighting PNPO, P2RY4, P2RX4 KMT2A 784/4885MAPT 433/4885CYP1A2 1772/4885
US-20180016491-A1 NEW CLASS OF ORGANIC PHOSPHORS BASED ON DERIVATIVES OF BENZIMIDAZOXANTHENOISOQUINOLINONE FOR LED LIGHTING PNPO, PPOX, PIR KMT2A 687/4885MAPT 406/4885CYP1A2 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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