Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689452 | 0.88 | GAA (0.49) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16689450 | 0.88 | GAA (0.47) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL1564819 | 0.87 | MAPT (0.59) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL3113232 | 0.86 | GAA (0.66) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16690704 | 0.86 | GAA (0.54) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16678767 | 0.86 | GAA (0.52) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL6031033 | 0.85 | GRM6 (0.44) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16689460 | 0.85 | ALDH1A1 (0.46) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL23827487 | 0.84 | GAA (0.53) | GAAALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16678709 | 0.83 | ALDH1A1 (0.54) | GAAALDH1A1MAPTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | disclosed |
| US-9278958-B2 | Anti-cancer compounds | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D (BE) | 2016-03-08 | — | — | US | disclosed |
| US-9278958-B2 | Anti-cancer compounds | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D (BE) | 2016-03-08 | — | — | US | disclosed |
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | UNIVERSITA DEGLI STUDI DI FERRARA (IT) | 2015-05-07 | — | — | US | disclosed |
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | UNIVERSITA DEGLI STUDI DI FERRARA (IT) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | ATP5F1A, TP53, ABCF1 | GAA 1316/4885ALDH1A1 266/4885MAPT 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.