Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 4/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689894 | 0.99 | CCR1 (0.33) | CCR1CCR5CCR8L3MBTL1KDM4E | |
| SCHEMBL13892744 | 0.87 | MEN1 (0.35) | — | |
| SCHEMBL13569556 | 0.87 | METAP1 (0.34) | CCR1CCR5CCR8L3MBTL1MAPK1 | |
| SCHEMBL19258041 | 0.87 | METAP1 (0.34) | CCR1CCR5CCR8L3MBTL1MAPK1 | |
| SCHEMBL13070346 | 0.87 | METAP1 (0.32) | METAP1CYP2C9 | |
| SCHEMBL13569543 | 0.86 | METAP1 (0.32) | METAP1 | |
| SCHEMBL16689839 | 0.86 | — | — | |
| SCHEMBL19258569 | 0.86 | METAP1 (0.35) | CCR1CCR5CCR8METAP1CYP2C9 | |
| SCHEMBL16689841 | 0.85 | IRAK4 (0.31) | — | |
| SCHEMBL4561419 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246351-B1 | COMPOUND HAVING PYRIDOINDOLE RING STRUCTURE BONDED WITH SUBSTITUTED PYRIDYL GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2015-05-06 | — | — | EP | disclosed |