Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 12/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13569556 | 1.00 | METAP1 (0.34) | METAP1DHODHTSHRMAPK1HSD17B10 | |
| SCHEMBL19258569 | 0.97 | METAP1 (0.35) | METAP1DHODHCTSDCYP2C9CCR1 | |
| SCHEMBL13569543 | 0.95 | METAP1 (0.32) | METAP1DHODHCTSD | |
| SCHEMBL13569500 | 0.92 | MCL1 (0.33) | METAP1TSHRHSD17B10CYP2C9CYP1A2 | |
| SCHEMBL13569600 | 0.91 | METAP1 (0.34) | METAP1CCR1CCR5CCR8 | |
| SCHEMBL13569478 | 0.90 | — | — | |
| SCHEMBL13569524 | 0.90 | ADORA3 (0.30) | ADORA3 | |
| SCHEMBL13569531 | 0.90 | CCR1 (0.32) | METAP1CCR1CCR5CCR8ADORA3 | |
| SCHEMBL13569630 | 0.89 | ADORA3 (0.31) | METAP1ADORA3 | |
| SCHEMBL13569467 | 0.89 | HTR2C (0.35) | METAP1MAPK1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128159-B1 | COMPOUND WHEREIN SUBSTITUTED BIPYRIDYL GROUP IS CONNECTED WITH PYRIDOINDOLE RING STRUCTURE THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2017-08-16 | — | — | EP | disclosed |